Robust and accurate sensor fusion algorithm using time of arrival data for acoustic event localization. The fusion algorithm compensates for incorrect measurements including multipath effects. The algorithm is capable of localizing multiple simultaneous sources with a high degree of accuracy.
This technology addresses the problem of designing and implementing online monitoring and diagnosis systems for complex hybrid systems by focusing on faults that occur in plant components and contains models where faults are represented by changes in system parameters. Hybrid systems are common in the avionics, spacecraft, automotive and robotics domains where behavior is characterized by continuous plant dynamics and discrete supervisory control. These hybrid systems require a tool that analyzes and seamlessly integrates multiple system models on a discrete and continuous basis. As a result, tasks like monitoring, fault diagnosis and control require model selection and switching to be performed online as system behavior evolves.
Contextualized feedback intervention and training protocol is a form assessment. It enables behavioral healthcare practitioners to assess and categorize the behavioral health status of patients in a mental health context. It also provides a training protocol for providers.
ListVUe is a software tool that permits the expeditious search of the United States Department of Commerce Export Control with a higher degree of accuracy than is currently available. This product is designed for any company or institution which is required to comply with U.S. export control laws and regulations.
This online program developed at Vanderbilt serves to centralize faculty information. Rocinante™ makes it easier to compile faculty data from across schools. The program is a powerful, easy to use tool that assists faculty in their administrative duties and in grant writing. The public view acts as a front-end web-site for each faculty member. Rocinante's most powerful feature is its ability to mine PubMed for faculty publications. This prevents faculty members from needing to manually link their publications to their information.
The Conflict of Interest Disclosure System ("CIDS") has been designed for use by universities, particularly those that conduct considerable academic research. CIDS provides an interface that permits faculty and staff to complete their conflict of interest disclosure on-line. It also permits the conflict of interest administrator to assign those who are responsible for approving conflict of interest disclosures and allows those approvers to review, return and/or approve an assigned employee's disclosure. CIDS provides recommended action plans for those reporting conflicts and an automated email reminder process.
The present invention is a method for assessing capillary permeability to determine vascular lung injury without requiring the injection of radioactive material or requiring the sampling of blood. The method includes measuring impedance and ultrasonic velocity of blood flow through a lung. A hypertonic bolus is injected into the blood flow, and measurements of the blood flow are taken to determine the ultrasonic velocity and the electrical impedance of the blood. These measurements are used to calculate the capillary transport quantity, which is the product of the reflection coefficient for movement of fluid across the capillary barrier and the filtration coefficient. The measured value of the capillary transport quantity can then be compared to a conventional capillary transport quantity for healthy lungs, and one can determine injury by a significant decrease in the measured capillary transport quantity as compared to the standard measurements. Furthermore, a comparison of the osmotic transient graphs of the plotted indicator curves can serve to acknowledge lung vascular injury. Lung injury can be determined from the measured data when the point of osmotic equilibrium (where the indicator curve crosses the baseline) is significantly delayed as compared to the point of osmotic equilibrium plotted for a healthy lung.
BCL::Commons:: (BioChemistry Library Commons) is an object oriented C++ programming library. The library is designed to simulate biological molecules - proteins and peptides in particular - as well as small chemicals such as therapeutics. It comprises mathematical methods to evaluate the energy of these molecules in their natural environment. BCL::Jufo is the first publicly released BCL::Commons module.
Vanderbilt engineers have developed a robust platform for point-of-care (POC) diagnostics applicable to infectious diseases, biowarfare agents and environmental and agricultural testing. This technology uses capture antibodies on a polyester filament, or DNA, on a gold wire that act as molecular hooks to troll for viral or bacterial protein antigens, RNA or capture DNA present in a small biological sample solution. It is envisioned that once the analytical POC device is purchased, a different single-use filament would be sold for each pathogen test of interest.
Vanderbilt researchers have discovered and patented a means of selectively expressing genes of interest in specific cells. This research tool allows an inactive nucleic acid to be delivered to a specific cell of interest and then the researcher can activate the nucleic acid by exposure to light. This system allows temporal controlled expression over exogenous nucleic acids only in targeted cells or selectively regulating endogenous gene expression.
Isolated nucleic acids encoding human SCN1A polypeptides, recombinantly expressed and isolated human SCN1A polypeptides, heterologous expression systems for recombinant expression of human SCN1A polypeptides, assay methods employing the same, and methods and compositions for modulation of sodium channel function.
The invention is a cell line (Human embryonic kidney 293) stably expressing a recombinant human cardiac voltage-gated sodium channel (hHl). The cells enable high throughput screening of compounds that modulate sodium channel activity.
Vanderbilt researchers and clinicians have developed a database and web application that tracks unborn fetuses as a separate patient population. Traditionally unborn fetuses are monitored and tracked for abnormalities and all of their information and documentation is placed within the mother's medical chart. This program creates a separate medical file for the unborn fetus that is linked to the maternal medical file. This system allows clinicians to easily sort and track unborn fetus abnormalities and easily identify treatment options that have shown to be beneficial to that patient population, ultimately improving clinical outcomes.