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128 available technologies

Stable Preparation of Fetal Hemoglobin to Improve Tissue Oxygenation

Dr. Hawiger and colleagues developed a novel form of cell-penetrating fetal hemoglobin. This technology is useful for the treatment of hemoglobinopathies or to increase oxygen delivery in any condition. The preparation is stable and sterile. Upon reconstitution, the treatment can be delivered I.V. or through transfusion.

Explore the Impact of Metabolic Dynamics in Cancer with 3-Hydroxybutyrate Cell Culture Media

D-3-Hydroxybutyrate (3-HB) cell culture medium is useful for studying cancer cells lines in a novel, but physiologically relevant, metabolic context. Cancer cells are known to have rapid glucose metaobolism and most cell-based research is carried out in glucose containing medium. Cancer cells alternatively use 3-HB as a carbon source, which is a prevalent metabolic substrate when fasting. 3-HB medium offers researchers the chance to study cell growth and chemotherapuetic agents in this novel and frequently overlooked context.

Generation of Neuroprogenitor Cells and Neurons from Human Induced Pluripotent Stem Cells by the Dorsomorphin Analog DMH1

This technology describes a novel methodology wherein human-induced pluripotent stem cells can be differentiated into neural precuror cells using DMH1 (a dorsomorphin analog). Neural progenitor cells can then be further differentiated into tyrosine hydroxylase expressing neurons.

Luciferase-expressing Embryonic Stem Cell Line for Monitoring wnt or BMP Promotor Activity

The mouse embryonic stem cell line, CGR8, has been genetically modified to express luciferase under the control of either the wnt or the BMP promoter system. This technology allows rapid visualization or genetic modification of wnt and BMP pathways in development.

Synthesis of Thallium-sensitive Fluorescent Dyes to Monitor Potassium Channel or Potassium-Dependent Transporter Activity

This technology describes a strategy for the synthesis of novel fluorescent thallium indicator dyes, which are useful for high throughput testing of potassium-dependent ion channel or transporter activity.

Antibodies to Leukocyte-Associated Immunoglobin-1 (LAIR-1)

Two rabbit anti-leukocyte-associated immunoglobin-1 (LAIR-1) polyclonal antibodies have been developed. Both intracellular (epitope 170-269) and extracellular (epitope 1-141) antibodies are available which can be used for immunoprecipitation and immunoblotting, respectively.

Antibody to Phospholipase C-gamma 2 (PLC)

Dr. Carpenter has created polyclonal anti-Phospholipase C-gamma 2 antibodies. Useful in the detection or immunoprecipitation of PLC-gamma2. This antibody is well established in the primary literature.

Subunit-Specific Antibodies to Adaptor Protein-2 (AP-2)

Dr. Carpenter's lab created antibodies which recognize either the alpha or beta subunit of Adaptor Protein-2. These antibodies are useful for researchers studying vesicle trafficking.

Human Transforming Growth Factor-Beta Type II (TGF beta) Receptor Antibody

Transforming growth factor (TGF) beta type II receptor antibodies directed towards the extracellular domain (epitope 4-19) are available from the laboratory of Harold Moses. TGF-beta-II plays an important role in several biological processes including developmental biology, cardiovascular biology and cancer.

Double Stranded RNA Specific Adenosine Deaminase (ADAR) Antisera

Emeson and colleagues have generated antisera to Double Stranded RNA Adenosine Deaminase (ADAR). ADAR has recently been shown to play critical roles in oncology and virology.

Purified bovine cAMP and cGMP dependant protein kinases

A Human DNA Helicase

Purified staphylocoagulase fragment (1-325)

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