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37 available technologies

Combined Raman Spectroscopy- Optical Coherence Tomography (RS-OCT)

Vanderbilt researchers have developed an optical system for the differentiation of normal and cancerous skin lesions. The system combines the diagnostic prowess of two separate techniques to provide non-invasive, real-time, in-situ evaluation of lesions.

Point of Care Device for Confirmation of Intravenous (IV) Catheter Placement and Measurement of Peripheral Venous Pressures

Vanderbilt researchers have designed a low-cost, point-of-care device that non-invasively monitors peripheral venous pressure (PVP) to ensure proper placement of peripheral intravenous (PIV) catheters in patients. Use of this device will ensure proper administration of intravenous fluids and intravenous drugs. The device will also prevent the administration of fluid and potent pharmacologic agents into the subcutaneous tissue or fascia, commonly known as "IV infiltration."

Solid-State Erbium Laser Surgical Cutting Probe

The present system developed by Vanderbilt researchers provides a combination of a base laser pump connected to a laser surgical probe via a connection assembly. The surgical probe has a disposable tip wherein the Er:YAG lasing occurs. This system is useful in laser surgeries involving high precision and appropriate power levels. In particular, intraocular surgeries could benefit from the use of such a system.

Catheter Having Temperature Controlled Anchor and Related Methods

Heart valve disease is the 3rd most prevalent source of cardiovascular disease, leading to approximately 20,000 deaths per year in the U.S. alone. Moreover, there are an estimated 41,000 mitral valve procedures performed in the U.S. each year. The only effective, long-term treatment for mitral valve disease is open-chest valve replacement surgery, which is highly undesirable for elderly patients. Thus, there is a pressing need to develop novel percutaneous strategies for treatment that will reduce the number of open-chest surgeries. David Merryman and colleagues have developed a new, combined catheter that uses cryo temperatures to adhere to moving mitral valve leaflets and radiofrequency ablation to alter the compliance of the leaflet tissue to prevent prolapse and regurgitation.

Adjustable Universal Platform for Surgical Navigation, Approach, and Implantation

A surgical platform usable for performing a surgical procedure. In one embodiment, the surgical platform comprises a base portion configured to receive at least one probe; a plurality of adjustable legs configured to support the base portion, each adjustable legs having a first end portion and an opposite, second end potion defining a length therebetween; and at least one movable portion configured to adjust the length of at least one adjustable leg.

Trimodal Handheld Probe Based on Raman Spectroscopy and Confocal Imaging for Cancer Detection

This technology relates to a device and method for non-invasive evaluation of a target of interest of a living subject, and in particular to devices and methods that integrate confocal imaging with confocal Raman spectroscopy, for non-invasive evaluation of the biochemical compositions and morphological details of normal and cancerous skin lesions of a living subject.

Helical Peristaltic Nanopump for BioMEMS Devices

A metering rotary nanopump for driving BioMEMS and microfluidic systems.

Optical Stimulation of the Auditory Nerve

A cochlear implant placed in a cochlea of a living subject for stimulating the auditory system of the living subject, where the auditory system comprises auditory neurons. In one embodiment, the cochlear implant includes a plurality of light sources, {L.sub.i}, placeable distal to the cochlea, each light source, L.sub.1, being operable independently and adapted for generating an optical energy, E.sub.i, wherein i=1, . . . , N, and N is the number of the light sources, and delivering means placeable in the cochlea and optically coupled to the plurality of light sources, {L.sub.i}, such that in operation, the optical energies {E.sub.i} generated by the plurality of light sources {L.sub.i} are delivered to target sites, {G.sub.i}, of auditory neurons, respectively, wherein the target sites G.sub.1 and G.sub.N of auditory neurons are substantially proximate to the apical end and the basal end of the cochlea, respectively.

Microcatheter with Hemodynamic Guide Structure

A catheter device for therapeutic and diagnostic use within a human vascular system in difficult to access locations such as bifurcating cerebral arteries. The distal end of the catheter body comprises a flexible material so that the catheter tip can deflect laterally towards the vessel wall in response to the hemodynamic lift. An intermediate section of the catheter body between the hub and the tip provides a semi-rigid control connection whereby pushing, pulling, and rotation of the hub produces a corresponding movement of the catheter tip.

System for Determining the Orientation of a Bone-Implanted Anchor

A method for simplifying the process of designing a platform for minimally invasive surgery. The platform is designed to attach to a set of bone-implanted anchors attached to the patient. This method makes the fitting of the platform to the anchors simpler and easier.

System for Determining the Orientation of a Bone Implanted Post

A method for determining an orientation of a base to which a fiducial marker is detachably mounted. The method includes the steps of determining the axis of symmetry for the fiducial marker and choosing the determined axis of symmetry of the fiducial marker as the axis of symmetry of the base.

Transductive Access Catheter

The tissue of the human body is separated by planes separated by minimal fluid, and it is often desirable to enter into the space between these planes to perform procedures including delivery or removal of fluid/therapeutics. Accurately and harmlessly placing catheters within these planes is very difficult because of the very close proximity of the tissues -- often within 1mm. The Transductive Access Catheter System solves these problems by allowing the operator to insert a shallow beveled needle into the space of interest using a hollow inner catheter that is filled with saline to probe much like a micro water hammer to detect difference in resistance to flow at the tip of the catheter. The primary competing technology uses suction to pull on the outer tissue which increases the target space volume at the catheter; however this has limitations of tissue rigidity and thickness (PerDUCER, Comedicus). Due to the versatility across disciplines, a wide variety of applications for this catheter exist, which include: Pericardial Space Infusion or Drainage, Pleural Space Infusion or Drainage, Subdural and Epidural Infusion, and Intraocular Fluid Space Infusion or Drainage.

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