Available Technologies

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295 available technologies

Free Standing Nanocrystal Thin Films

Vanderbilt researchers have developed a process that creates free standing nanocrystalline thin films using a simple, robust and cost- efficient process. This paves the way for manufacturing conformal films of nanocrystals at a fraction of the cost as compared to techniques currently used. The process could be applied in the manufacture of a number of end products such as solar cells supercapacitors, magnetic storage, semiconductor devices and catalysis.

Enhanced Cooling of Oil Based Transformers and Other Heat Generating Equipment with NanoParticle Suspensions

Nanometer-sized, low-cost, readily available, particulate nanodiamond is used as an additive to the mineral oil used in electrical power transformers and other oil-cooled electrical equipment to enhance the thermal conductivity [TC] and dielectric properties of the oil without compromising the oil's required electrical insulation, such that failures are suppressed, oil life is greatly extended and load boundaries are elevated. This could extend transformer life and allow increases to transformer MVA ratings.

High Bandwidth, Hot Gas and Liquid, Rotary Proportional Valves

These valves enable high-bandwidth proportional control of cold gas, hot gas, and/or liquid flow in relatively low-cost packages. With regard to 2-way liquid valves, there are no comparable products on the market (i.e., commercially available valves in this size range are on/off valves, which do not provide adequate control resolution for many applications). With regard to gas valves, all known cold gas 3-way and 4-way servovalves are linearly actuated, which increases cost and size and decreases performance relative to our designs. Further, there are no hot gas control valves in this size category on the market.

Synthetic Beam Chopper

Optical beam choppers have numerous applications and are ubiquitous in scientific and industrial equipment. The present technology improves the state-of-the-art for modulation and lock-in amplifi cation using mechanical beam choppers. The system achieves world class performance with lower limits of detection, decreased need for mechanical precision and decreased cost. Because of the high performance and low cost, the system may replace existing technology in current applications, and it may also enable the development of new products that are not currently feasible or economical with current technology.

Diamond Triode Devices with a Diamond Microtip Emitter

This technology is a diamond triode for micro and power electronics. Diamond microtip field emitters are used in triode vacuum electronic devices, sensors and displays. Diamond triode devices having integral anode and grid structures are fabricated using a patented process. Ultra-sharp tips are formed on the emitters in the fabrication process in which diamond is deposited into mold cavities in a two-step deposition sequence. During deposition of the diamond, the carbon graphite content is carefully controlled to enhance emission performance. The tips or the emitters are treated by post-fabrication processes to further enhance performance.

High Inertance, Low Mass Free Piston

Vanderbilt inventors propose a free piston system that provides high inertance and tunable dynamics.

SERS Template Fabricated from Patterned Nanoporous Gold

Vanderbilt researchers have developed a technique that will amplify the Raman scattering signal from adsorbed molecules on a roughened metal surface to enable unique identification of the adsorbed molecules.

Pepetide therapeutic for the treatment of hyperlipidemia and atherosclerosis

Atherosclerosis is a serious health concern; leading to 1.5 million heart attacks in the US each year and 795,000 strokes. Vanderbilt researchers have developed a peptide therapeutic that reduces atherosclerosis by 63% in mice fed a western diet. This peptide's unique mechanism attacks the problem at the level of gene expression, returning lipid synthesis to homeostasis, while also reducing cholesterol, triglyceride levels and improving liver function.

Biohybrid, Photoelectrochemical Energy Conversion Device Based on Photosystem I Deposited Silicon Electrodes

Summary: Aresearch team at Vanderbilt University have developed a biohybrid, photoelectrochemical energy conversion device with multilayer films of Photosystem I (PSI) deposited on silicon electrodes, which yielded an average photocurrent density of 875 µA/cm2; one of the highest reported photocurrent densities for a film of PSI deposited onto an electrode of any material.

Near-Infrared Dye with Large Stokes Shift for Simultaneous Multichannel in vivo Molecular Imaging

Fluorescent labels having near-infrared (NIR) emission wavelengths have the ability to penetrate tissue deeper than other emission wavelengths, providing enormous potential for non-invasive imaging applications. However, advancement of optical imaging (particularly NIR imaging) is hindered by the limitation of narrow Stokes shift of most infrared dyes currently available in the market. Vanderbilt researchers have developed a novel NIR dye (4-Sulfonir) for multichannel imaging that enables in vivo imaging of multiple targets due to its large Stokes shift. 4-Sulfonir with its unique large Stokes shift (~150 nm) and wide excitation spectrum could be used in parallel with other NIR dyes for imaging two molecular events simultaneously in one target.

Novel Target Regulating Angiogenesis

Vanderbilt scientists have discovered that the receptor tyrosine phosphatase DEP-1 plays a significant role in angiogenesis and that modulation of the DEP-1 receptor with certain agents can affect endothelial cell growth. The research team has developed antibodies that bind to the ectodomain of a mammalian transmembrane protein known as DEP-1 (for density enhanced protein) or CD148. CD148 (also named DEP-1/PTPn) is a receptor-like protein tyrosine phosphatase that is abundantly expressed in vascular endothelial cells, hematopoietic-cell lineages, duct epithelia of thyroid, mammary and gastrointestinal tissues.

On Chip Polarimetry for HTS

Using microfluidic technology developed by the Bornhop Lab at Vanderbilt, this invention enables the rapid determination of the optical activity of compounds and solutions. Due to the nature of this invention, it is possible to screen a multitude of samples in a high throughput manner in less time with less material and greater accuracy than the industry standards.

A Method for Regulating Glucokinase by Reaction With Nitric Oxide

Vanderbilt researchers have discovered a novel mechanism through which the insulin regulating enzyme glucokinase is regulated. This discovery provides a powerful way to screen for activators of glucokinase, which may lead to therapies for diabetes.

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