Oncology

Novel Fused Heterocyclic Compound as Selective BMP Inhibitors

Licensing manager: 
Mike Villalobos
Read more

Gene Signature Diagnostic to Measure LKB1 Loss and MEK Inhibitor Sensitivity

A Vanderbilt research group has discovered a diagnostic to identify patients with non-small cell lung cancer that would respond to MEK inhibitor therapies. This diagnostic indirectly measures loss of tumor suppressor activity by the protein LKB1. The traditional approach to determine MEK inhibitor sensitivity, which is measurement of LKB1 mutations, misses 50% of patients who would benefit from these drugs. This diagnostic measures expression of a small panel of genes to identify a larger population that is sensitive to MEK inhibition.

Description of Technology

A Vanderbilt research group has discovered a diagnostic to identify patients with non-small cell lung cancer that would respond to MEK inhibitor therapies.

Licensing manager: 
Mike Villalobos
Read more

Primary human fibroblats derived from prostate cancer tissue and normal tissue

This research targets prostate cancer.
Licensing manager: 
Karen Rufus
Read more

MEF cell line derived from histone deacetylase-3 conditiontal knockout mice

This research targets HDAC-3.
Licensing manager: 
Hassan Naqvi
Read more

HCC2429 Human Lung Cancer Cell Line

This research targets HCC2429.
Licensing manager: 
Karen Rufus
Read more

Mouse cDNA for CrK-associated substrate

This research targets Cas.
Licensing manager: 
Jody Hankins
Read more

Mouse Focal Adhesion Kinase cDNA

This research targets FAK.
Licensing manager: 
Jody Hankins
Read more

B53 CHO cell line with inducible VDJ recombinase expression

This research targets VDJ recombinase.
Licensing manager: 
Karen Rufus
Read more

Screening assay for molecules that alter cell cycle rhythm

This research targets Cell Cycle.
Licensing manager: 
Hassan Naqvi
Read more

Slot-Slot Assay for Malonaldehyde-Deoxyguanosine Adducts in DNA

This research targets DNA adducts.
Licensing manager: 
Mike Villalobos
Read more

Featured Video

Vanderbilt Patent Activity

View Vanderbilt University Patents

CTTC on Twitter