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  1. Enzyme protects against obesity-related heart disease

    ... Saturated fats found in high-fat diets increase the risk of heart failure. Now Manisha Gupte, PhD,  Hind Lal , PhD, and colleagues show ... a high-fat diet, the knockout mice developed severe heart disease compared to normal controls even though there was no difference in ...

    sommers - 06/18/2018 - 9:44am

  2. Discovery of natural compound may help fend off antibiotic resistance of hard-to-treat infections

    ...  bacteria. Bachmann is working with the  Center for Technology Transfer and Commercialization  to explore development for ... Endowment Fund and grant 12GRNT11920011 from the American Heart Association. Scanning electron microscopy was performed at the VUMC Cell ...

    sommers - 08/19/2020 - 6:47pm

  3. Tech Connect, Vol. 7, Issue 12: Vanderbilt Inventor wins ASPET Award

    ... ASPET said Lindsley was honored for “his pioneering use of technology-enabled synthesis, which led to fundamental and transforming effects ... positive allosteric modulators of muscarinic acetylcholine receptor M1 ...

    steelmk - 07/21/2017 - 3:09pm

  4. Immunotherapies linked to specific heart complications

    ... inhibitors, Vanderbilt researchers have shown that heart and vessel complications include myocarditis, pericarditis, vasculitis ... the cancer cells, in rare situations it can also attack the heart and vessels, and in some cases, this can result in fatalities,” said ... study advises clinicians to monitor for pericardial disease and vasculitis. Javid Moslehi , MD, director of the ...

    sommers - 02/21/2019 - 9:51am

  5. Tech Connect, Vol. 7, Issue 22: Forum highlights innovative approaches to bolstering biomedical research

    ... Bentley, M.S., assistant vice chancellor for the Center for Technology Transfer and Commercialization, described how his center, which ... allosteric modulators of the muscarinic acetylcholine receptor M4 9,636,399    Anti-factor XI monoclonal antibodies and ...

    steelmk - 07/21/2017 - 3:39pm

  6. Vanderbilt vaccine pioneer James Crowe honored with major science prize

    ... Vaccine Center , will be honored today by the science and technology company Merck KGaA, Darmstadt, Germany for his contributions to ... that should make it possible to swiftly detect, treat and prevent the spread of emerging pathogens, “and in doing so protect humanity ...

    sommers - 07/17/2019 - 11:16am

  7. Tech Connect, Vol. 6, Issue 16: CTTC participates at AUTM 2016

    ... participates at AUTM 2016 Each year, thousands of technology transfer officers convene with professionals from a variety of ...       Substituted pyrazolo[1,5-a]pyrazines as mGluR5 receptor modulators 9,252,445       Nanofiber ...

    steelmk - 11/10/2016 - 7:45am

  8. Eight Vanderbilt technologies earn patent protection in December

    ... Allosteric Modulators of the Muscarinic Acetylcholine Receptor M1  Aaron Bender  Jeff Conn  Julie Engers ...

    sommers - 01/17/2024 - 10:45am

  9. Tech Connect, Vol. 6, Issue 4: Vanderbilt University and La Jolla Pharmaceutical Company enter Exclusive Research and License Agreement

    ... is to research and develop small-molecule BMP type-I receptor inhibitors designed to aid in treatment of rare genetic disorders. ... equipment supplier regarding Doppler Ultrasound Phantom technology developed by Jared Grice from the Department of Radiology ...

    steelmk - 11/15/2016 - 4:19pm

  10. Early effort to thwart chikungunya infection shows positive results

    ... it in a lipid nanoparticle using in their proprietary technology. Pre-clinical studies suggested that once injected, cells will take ... outlined adverse effects including transient elevated heart rate observed in one of the participants given the highest dose of ...

    sommers - 09/27/2019 - 9:55am