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  1. Dolly Parton Makes Generous Gift to Advance COVID-19 Research at Vanderbilt

    ... she said. "I felt like this was the time for me to open my heart and my hand, and try to help.” VUMC’s researchers are testing an ... on entirely new therapies that could effectively treat and prevent the infection. Both strategies are aimed at providing a bridge for ...

    sommers - 04/07/2020 - 10:42am

  2. Research Snapshot: Mosquito larvae are surprisingly complex

    ... complex mosquito larvae. Looking further into how the larval receptor neurons work may provide insights into how they act in the adult ... of commercial products with guidance from the  Center for Technology Transfer and Commercialization . FUNDING This work was ...

    sommers - 09/15/2021 - 4:06pm

  3. Team explores diabetes drug’s ability to treat RSV infection

    ... from the pancreas by activating the glucagon-like peptide 1 receptor (GLP-1R). “The connection between GLP-1R signaling and lung ... for RSV bronchiolitis can receive the drug palivizumab to prevent RSV infection, but there are no treatment options after RSV infection ...

    sommers - 07/13/2018 - 9:56am

  4. Seven Vanderbilt technologies earn patent protection in January

    ...  Fluidic Device for the Detection, Capture, or Removal of a Disease Material  Charleson Bell  Andrew Cook  Todd ... Allosteric Modulators of the Muscarinic Acetylcholine Receptor M4  Logan Baker  Jeff Conn  Darren Engers ...

    sommers - 02/01/2024 - 12:21pm

  5. Flu’s “hidden target” may lead to universal vaccine: study

    ... influenza A virus that could lead to better ways to prevent and treat the flu. Because influenza A viruses such as H1N1 and ... the United States died from flu-related complications. A receptor binding site on the surface of the influenza virus enables it to ...

    sommers - 05/20/2019 - 1:02pm

  6. Targeting diabetic kidney disease

    ... previously showed that the epidermal growth factor receptor (EGFR) is activated in mouse models of type 1 diabetes, and that drugs which inhibit EGFR prevent the development of DN. EGFR becomes active when phosphate ...

    sommers - 02/21/2019 - 9:51am

  7. Team’s findings show glutamine metabolism affects T cell signaling

    ... metabolism — like blocking glucose metabolism — would prevent T cell activation and function. They used a drug that inhibits the ... used the drug in a mouse model of CAR (chimeric antigen receptor) T-cell therapy. CAR T cells are cancer-killing T cells that have been ...

    sommers - 02/21/2019 - 9:51am

  8. Tech Connect, Vol. 7, Issue 18: Vanderbilt Vaccine Center antibody effectively treats Marburg virus in monkeys

    ... The Center for Technology Transfer and Commercialization (CTTC) is working with AdvaMed , ... allosteric modulators of the muscarinic acetylcholine receptor M1 ...

    steelmk - 07/21/2017 - 3:31pm

  9. VUMC chikungunya antibody set to enter clinical trial

    ... it in their proprietary lipid nanoparticle (LNP) technology, which has been delivered in a Phase I safety trial in human ... for chikungunya virus infection and no licensed vaccine to prevent it. Enabling the body to produce antibodies against chikungunya through ...

    sommers - 02/27/2019 - 2:41pm

  10. Biophotonics device for parathyroid ID wins R&D 100 Award

    11/05/2019 An optical imaging technology developed by Orrin H. Ingram Professor of Biomedical Engineering ... blood calcium levels in the human body to support normal heart, nervous system, kidney, and bone function. These four tiny glands are ...

    sommers - 11/05/2019 - 3:37pm