By CHRIS DUNCAN
AP Sports Writer

LEXINGTON, Ky. - Derek Abney set an NCAA record with his sixth kick return for a score this season as Kentucky beat Vanderbilt 41-21 Saturday.

Artose Pinner ran for a career-high 224 yards and four touchdowns for Kentucky (7-4, 3-4 SEC). Pinner set a school record with his eighth 100-yard rushing game of the season. His four TD runs tied a school record.

Abney set the record in the first quarter when he followed blockers down the sideline, outran a trio of pursuers and dove for the end zone pylon for a 95-yard touchdown.

In addition to the NCAA record, Abney set an SEC record with his seventh career kick return for a touchdown.

Jay Cutler threw for 176 yards and two touchdowns to lead Vanderbilt (2-9, 0-7), which lost its 16th straight conference game.

The Wildcats led 28-21 and took possession at their own 25 with 4:32 left in the game. Pinner rushed nine times for 82 yards on the decisive drive, finishing it with a 1-yard touchdown dive with 16 seconds left. Pinner, the SEC's top rusher, became the fifth Wildcat to go over 2,000 career yards rushing.

Kentucky defensive end Otis Grigsby recovered a botched snap in the end zone on the game's final play.

The Wildcats didn't take long to reach the end zone against the league's worst scoring defense, driving 68 yards for a touchdown on the game's first possession. Pinner finished the march with a 23-yard touchdown run.

Vanderbilt's Jonathan Schaub intercepted a deflected pass by Jared Lorenzen at midfield later in the first quarter, snapping the Kentucky quarterback's school-record streak of 152 passes without a pick.

It was only the Commodores' 10th forced turnover of the season and led to Cutler's 38-yard touchdown pass to tight end Tom Simone.

The 7-7 tie didn't last long. Abney's kickoff return broke the tie, and a Vanderbilt fumble set up a 2-yard touchdown run by Pinner less than two minutes later.

Pinner was over 100 yards rushing early in the second quarter. He added a 16-yard touchdown run with 10:39 left in the first half for a 28-7 Kentucky lead.

Dan Stricker made a one-handed touchdown catch with 11 seconds left in the first half cut the deficit to 28-14.

The Wildcats' offense spent much of the third quarter in Vanderbilt territory but came away with no points. Taylor Begley was ready to try a 45-yard field goal with 4:51 left, but Glenn Pakulak bobbled the snap and the Commodores took over.

Kwane Doster had a 39-yard run to the Kentucky 1 and Cutler scored on a fourth-down sneak in the quarter's final minute to make it 28-21.

Lorenzen threw his second interception to Herdley Harrison at the Vanderbilt 43 with 5:35 left, but the Commodores couldn't take advantage.