The VIIBRE Automated Biosystems Core (ABC) offers acquisition of multi-parameter quantitative data sets of cell populations and individual cells with great statistical validation power, automated analysis routines that discern small changes, and linked events in high volumes.
VIIBRE's PerkinElmer Opera QEHS is a state-of-the-art, high-throughput, high-content confocal screening microscope. It provides ultra-fast, high-resolution imaging of 96, 384, and 1536 wellplates, glass slides, or VIIBRE's custom microfluidic wellplates and zebrafish holders.
The instrument is capable of acquiring about 80 to 400+ images (1.3 MP, 12-bit confocal) per minute depending on your imaging setup. It utilizes up to 4 CCD cameras (3 Peltier-cooled), 4 lasers (405, 488, 561, 640 nm) plus a tunable UV/Vis source and TLED-brightfield illumination.
The confocal spinning-disk technique with 40 ms minimum exposure times allows for minimal bleaching ofyour samples, while taking high-quality images at very high frame rates, which makes it ideal for live cell imaging. A multitude of optical filters and the option to separate or combine exposures meet a wide range of fluorescent labeling needs.
For questions regarding grant information, Screening4Hire, training, and assay setup or to schedule the instrument, please contact ABCmanager@vanderbilt.edu .
