Ginseng
Another ingredient in Metabolife is Ginseng root, "a traditional oriental medicine" with many different components (Mogil et al, 1998). The actual purpose of the Ginseng in the herbal supplement is unspecified; Ginseng is most commonly known for it's energy-reviving attributes, however. Additionally, many assertions suggest that ginseng could play a role in treatment of motion sickness.  More studies have been done to this second effect than to the first.
Mogil and associates determined that low to moderate doses of Ginseng extract lead to hypothermia, and antagonism of pharmacological actions of morphine. This was a conclusion of a study of ginseng and pain in rats (1998). Another study by Phillips, Hutchinson, and Ruggier published in Anaesthesia examined the affect of ginger on the gastric emptying rate. The results of this study indicated that not only did ginger have no apparent affect upon the gastric emptying rate, but "no [other] adverse affects [to ginseng] were noted" either (1998). Therefore, ginseng may not pose an immediate threat to consumers, but nor is their any certainty as to the role it plays in the Metabolife substance. However, the abstract of Yuan, Wu, Lowell, and Gu's study on the  "gut and brain effects of American ginseng root on brainstem neuronal activities in rats" suggested that
 after [aqueous extracts of American ginseng root] application to the gastric or brainstem compartment, a concentration- related inhibition in neuronal discharge frequency in the brainstem unitary activity was observed, suggesting that [ginseng] may play an important role in regulating the digestive process and modulating brain function. (1998)
This is perhaps that only current explanation derived from the information obtained. All other studies tended to focus on motion sickness and whether or not ginseng was a valid treatment for motion sickness.


 


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