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Contrast Enhanced Spectroscopic Detection of Oral Cancer  
On-Chip Interferometry  
Lanthanide Chelate Multi-modal Molecular Imaging Agents  
C&E News Citation on Microscale Polarimetry (PDF)  
 

 

 

 

 

 



Amanda KussrowAmanda Kussrow

My Research:
My work involves using the BIRC system to study protein binding in a variety of systems, such as protein-protein, protein-antibody, and protein-carbohydrate, in a free-solution label-free format. BIRC has shown very high sensitivity and I have been able to show detection limits for proteins in the picomolar range. This sensitivity and the small probe volumes used in BIRC greatly reduces the amount of sample used, thus allowing kinetic information to be more easily determined about a protein that is difficult and expensive to make. Another application that I am involved in is the development of a method for disease diagnosis using the BIRC system. I have also been trained in the cleanroom and am able to synthesize chips for use in the BIRC system from poly(dimethyl)siloxane (PDMS).

About Me:
I was born and raised in Maryland, just outside of Baltimore, where most of my family still lives. I received my BS in chemistry from Villa Julie College in 2003 and joined the Bornhop group in 2004 after my first semester at Vanderbilt University. When not in the lab, I am spending time with my pets, Maverick, a German shepherd, and Squire, a quarter horse. I have been riding horses since I was seven and have had my horse for over nine years now.

 


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