you are not logged in
Login in Help | Return to Main
 
Helpful Links
Research
Michael P. Stone
Group Members
Publications
News & Events
Contact Us
 

Selected Publications

Reference
Huang, H., Wang, H., Qi, N., Lloyd, R.S., Harris, T.M., Rizzo, C.J., & Stone, M.P. (2008) "The Stereochemistry of trans-4-Hydroxynonenal-derived Exocyclic 1,N2-Deoxyguanosine Adducts Modulates Formation of Interstrand Cross-links in the 5'-CpG-3' Sequence." Biochemistry 47, 11457-11472. PMID: 18847226
Minko, I.G., Kozekov, I.D., Harris, T.M., Rizzo, C.J., Lloyd, R.S., & Stone, M.P. (2009) "Chemistry and Biology of DNA Containing 1,N2-Deoxyguanosine Adducts of the alpha,beta-Unsaturated Aldehydes Acrolein, Crotonaldehyde, and 4-Hydroxynonenal " (2009) Chem. Res. Toxicol. 22, 759-778. 177 references. PMID: 19397281 PMCID: PMC2685875
Voehler, M.W., Eoff, R.L., McDonald, W. H., Guengerich, F.P., & Stone, M.P. "Modulation of the Structure, Catalytic Activity, and Fidelity of African Swine Fever Virus DNA Polymerase X by a Reversible Disulfide Switch." (2009) J. Biol. Chem. 284, 18434-18444. PMID: 19419958 PMCID: PMC2709365
Xu, W., Merritt, W.K., Nechev, L.V., Harris,T.M., Harris, C.M., Lloyd, R.S., & Stone, M.P. "Solution Structure of the 1,4-Bis(2'-Deoxyadenosin-N6-yl)-2S,3S-butanediol Crosslinked Adduct Arising from Butadiene Diepoxide in the Human N-ras Codon 61 Sequence." (2007) Chem. Res. Toxicol. 20, 187-198.
Cho, Y.-J., Jacob, J., Voehler, M., Kim, H.-Y., Kozekov, I., Harris, T.M., & Stone, M.P. "Stereochemistry Modulates the Stability of Reduced Interstrand Cross-Links Arising from R- and S-α-CH3-γ-OH-1,N2-Propano-2'-deoxyguanosine in the 5'-CpG-3' DNA Sequence." (2007) Biochemistry 46, 2608-2621.
Brown, K.L., Adams, T., Jasti, V.P., Basu, A.K., & Stone, M.P. Interconversion of the cis-5R,6S- and trans-5R,6R-Thymine Glycol Adducts in Duplex DNA." (2008) J. Am. Chem. Soc. 130, 11701-11710. PMID: 18681438
Brown, K.L., Adams, T., Jasti, V.P., Basu, A.K., & Stone, M.P. (2008) "Interconversion of the cis-5R,6S- and trans-5R,6R-Thymine Glycol Adducts in Duplex DNA." J. Am. Chem. Soc. 130, 11701-11710. PMID: 18681438
Brown, K.L., Basu, A.K., & Stone, M.P. "The cis-(5R,6S)-Thymine Glycol Lesion Occupies the Wobble Position When Mismatched with Deoxyguanosine in DNA." (2009) Biochemistry 48, 9722-9733. PMID: 19772348 PMCID: PMC2761728
Brown, K.L., Bren, U., Stone, M.P., & Guengerich, F.P. "Inherent Stereospecificity in the Reaction of Aflatoxin B1 8,9-Epoxide with Deoxyguanosine and Efficiency of DNA Trapping." (2009) Chem. Res. Toxicol. 22, 913-917. PMID: 19301826
Ganguly, M., Wang, F., Kaushik, M., Stone, M.P., Marky, L.A., & Gold, B. "A Study of 7-Deaza-2'-Deoxyguanosine•2'-Deoxycytidine Base Pairing in DNA." (2007) Nucleic Acids Res. 35, 6181-6195.
Brown, K.L., Bren, U., Stone, M.P., & Guengerich, F.P. Inherent Stereospecificity in the Reaction of Aflatoxin B1 8,9-Epoxide with Deoxyguanosine and Efficiency of DNA Trapping." (2009) Chem. Res. Toxicol. 22, 913-917. PMID: 19301826
Brown, K.L., Voehler, M.W., Magee, S., Harris, C.M., Harris, T.M., & Stone, M.P. "Structural Perturbations Induced by the a-Anomer of the Aflatoxin B1 Formamidopyrimidine Adduct in Duplex and Single-Strand DNA." (2009) J. Am. Chem. Soc. 131,16096-16107. PMID: 19831353 PMCID: PMC2773149
Huang, H., Wang, H., Lloyd, R.S., Harris, T.M., Rizzo, C.J., & Stone, M.P. "Conformational Interconversion of the trans-4-Hydroxynonenal-Derived (6S,8R,11S) 1,N2-Deoxyguanosine Adduct When Mismatched with Deoxyadenosine in DNA." (2009) Chem. Res. Toxicol. 22, 187-200. PMID: 19053179
Huang, H., Wang, H., Lloyd, R.S., Harris, T.M., Rizzo, C.J., & Stone, M.P. "Conformational Interconversion of the trans-4-Hydroxynonenal-Derived (6S,8R,11S) 1,N2Deoxyguanosine Adduct When Mismatched with Deoxyadenosine in DNA." (2009) Chem. Res. Toxicol. 22, 187-200. PMID: 19053179 PMCID: PMC2701371
Dexheimer, T.S., Rizzo, C.J., Stone, M.P., & Pommier, Y. "The Modulation of Topoisomerase I Cleavage and the Induction of DNA-Topoisomerase I Crosslinks by Crotonaldehyde-derived DNA Adducts." (2008) Nucleic Acids Res. 36, 4128-4136. PMID: 18550580
Huang, H., Wang, H., Qi, N., Lloyd, R.S., Harris, T.M., Rizzo, C.J., & Stone, M.P. "Rearrangement of the (6S,8R,11S) and (6R,8S,11R) Exocyclic 1,N2-Deoxyguanosine Adducts of trans-4-Hydroxynonenal to N2-Deoxyguanosine Cyclic Hemiacetals When Placed Complementary to Cytosine in Duplex DNA." (2008) J. Am. Chem. Soc. 130, 10898-10906. PMID: 18661996
Shanmugam, G., Goodenough, A.K., Kozekov, I.D., Harris, T.M., Guengerich, F.P., Rizzo, C.J., & Stone, M.P. "Structure of the 1,N2-Ethenodeoyguanosine Adduct Opposite Cytosine in Duplex DNA: Hoogsteen Base Pairing at pH 5.2." (2008) Chem. Res. Toxicol. 21, 1795-1805. PMID: 18693701
Stone, M.P., Cho, Y.-J., Huang, H., Kim, H.-Y., Kozekov, I.D., Kozekova, I., Wang, H., Lloyd, R.S., Harris, T.M., & Rizzo, C.J. "Interstrand DNA Cross-links Induced by a,b-Unsaturated Aldehydes Derived from Lipid Peroxidation and Environmental Sources. (2008) Acc. Chem. Res. 41, 793-804. PMID: 18500830
Wang, F., Li, F., Ganguly, M., Marky, L.A., Gold, B., Egli, M., & Stone, M.P. "A Bridging Water Anchors the Tethered 5-(3-aminopropyl)-2¢-Deoxyuridine Amine in the DNA Major Groove Proximate to the N+2 C•G Base Pair: Implications for Formation of Interstrand 5¢-GNC-3¢ Cross-links by Nitrogen Mustards." (2008) Biochemistry 47, 7147-7157. PMID: 18549246
Wang, Y., Musser, S.K., Saleh, S., Marnett, L.J., Egli M., & Stone, M.P. "Insertion of dNTPs Opposite the 1,N2-Propanodeoxyguanosine Adduct by the Sulfolobus solfataricus P2 DNA Polymerase IV." (2008) Biochemistry 47, 7322-7334.
Elmquist, C.E., Wang, F., Stover, J.S., Stone, M.P., & Rizzo, C.J. "Conformational Differences of the C8-Deoxyguanosine Adduct of 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) Within the NarI Recognition Sequence." (2007)
Wang, F., Elmquist, C.E., Stover, J.S., Rizzo, C.J., & Stone, M.P. "DNA Sequence Modulates Conformation of C8-dG Adducts of the Food Mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) in Duplex DNA." (2007) Biochemistry 46, 8498-8516.
Wang, Y., Schnetz-Boutaud, N.C., Saleh, S., Marnett, L.J., & Stone, M.P. "Bulge Migration of the Malondialdehdye OPdG DNA Adduct When Placed Opposite a Two-Base Deletion in the (CpG)3 Frameshift Hotspot of the Salmonella typhimurium hisD3052 Gene." (2007) Chem. Res. Toxicol. 20, 1200-1210.

 

 


Stone Group
Vanderbilt University Department of Chemistry
© 2006 Vanderbilt University